E-ISSN 2602-4837
The Turkish Journal of Ear Nose and Throat Chronic mastoiditis associated with leukocyte adhesion deficiency type 1: A case report [Tr-ENT]
Tr-ENT. 2018; 28(1): 48-51 | DOI: 10.5606/Tr-ENT.2018.98608

Chronic mastoiditis associated with leukocyte adhesion deficiency type 1: A case report

Cömert Şen, Can Doruk, Mehmet Çelik, Levent Aydemir, Kadir Serkan Orhan
Department of Otolaryngology & Head and Neck Surgery, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey

Adhesion molecules work for leukocytes to infiltrate to the site of inflammation. Deficiencies of these molecules can disturb neutrophil migration and thus inflammation. This group of illnesses is named leukocyte adhesion deficiency (LAD) syndromes. Mastoiditis is a very rare and unexpected complication. CD 18 count is the prognostic factor and might affect the treatment modalities. We report the case of a six-year-old girl with LAD type 1 who presented with chronic mastoiditis and the treatment of this unusual presentation.

Keywords: Chronic middle ear disease, leukocyte adhesion deficiency, pediatric ear disorders, pediatric mastoiditis, primary immunodeficiency syndromes.

Cömert Şen, Can Doruk, Mehmet Çelik, Levent Aydemir, Kadir Serkan Orhan. Chronic mastoiditis associated with leukocyte adhesion deficiency type 1: A case report. Tr-ENT. 2018; 28(1): 48-51

Corresponding Author: Can Doruk, Türkiye
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